5T4-HM401F-100μg / 询价
5T4-HM401F-500μg / 询价
5T4-HM401F-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant FITC-Labeled Human TPBG/5T4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser32-Ser355 [Accession | Q13641-1]. |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. |
波长(Wavelength)
|
Excitation Wavelength: 490 nm Emission Wavelength: 520 nm |
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
制剂(Formulation)
|
Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
存储(Storage)
|
Valid for 6 months from date of receipt when stored at -80°C. |
Recombinant FITC-Labeled Human TPBG/5T4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser32-Ser355 [Accession | Q13641-1].
The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Excitation Wavelength: 490 nm
Emission Wavelength: 520 nm
> 95% as determined by Bis-Tris PAGE
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Valid for 6 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
M6P1; 5T4AG; WAIF1; TPBG; 5T4
(1) Harrop R, O'Neill E, Stern PL. Cancer stem cell mobilization and therapeutic targeting of the 5T4 oncofetal antigen. Ther Adv Vaccines Immunother. 2019 Jan 25;7:2515135518821623. doi: 10.1177/2515135518821623. PMID: 30719508; PMCID: PMC6348545.
5T4-HM401F-100μg / 询价
5T4-HM401F-500μg / 询价
5T4-HM401F-500μgx2 / 询价
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